The Papers

PrimalBasics · Research and Methodology

The Papers

Mechanistic arguments and methodology, in long form.

PrimalBasics publishes long-form pieces that engage seriously with the science behind the formulations — and behind the choices we made not to formulate. Each paper takes a clear position, documents the reasoning, and cites the published literature it rests on.

A Paper · May 2026 · PrimalDent

Conditions Over Ingredients

A Mechanistic Case for Upstream Prevention in Oral Care

Hydroxyapatite has become the dominant active ingredient across clean-beauty oral care. We evaluated whether to add it to a reformulated PrimalDent — including a Japanese eggshell-derived supplier — and decided not to. This paper documents why: a mechanistic argument for upstream prevention over downstream remediation, with citations.